Conjugated linoleic acid (CLA) is known best for its weight loss properties, but a recent study in the Clinical Nutrition Journal suggests it may also benefit intestinal health. The study, coauthored by researchers at Virginia Tech University, the University of North Carolina, and Wake Forest University School of Medicine, indicated that CLA supplementation may help people living with Crohn’s disease manage bowel inflammation.
Crohn’s disease is a chronic immune-inflammatory condition which involves the gastrointestinal tract. Although the causes of the disease remain a mystery, scientists have found evidence of both genetic and environmental triggers resulting in this type of immune dysregulation. Intestinal inflammation is exceptionally painful, but CLA may work to help suppress pro-inflammatory compounds.
Results showed CLA supplementation correlated with drops in certain types of T-cell levels in the blood commonly associated with inflammation. For patients in the study, disease severity as measured by the Crohn’s disease activity index (CDAI) was significantly improved, showing a drop in CDAO from 245 to 187 over the 12-week period.
The present study has shed new light on the clinical potential of this compound and provided insights on the possible mechanisms of immune modulation targeted by CLA in the human system” wrote researchers.
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